Indications
Magmil suspension is used in
constipation, heart burn, gas and nausea. It is also indicated in acute and
long acting constipation due to hyper acidity and peptic ulcer or stomatitis.
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Pharmacology
Magnesium Hydroxide is popularly
known as Milk of Magnesia. It is a mildly acting antacid and laxative. It is
poorly and slowly absorbed and acts by its osmotic properties in the luminal
fluid which causes retention of fluid in the bowel. It is useful for emptying the
bowel prior to surgical, radiological and colonoscopic procedures and can help
to eliminate parasites following appropriate therapy and toxic material in some
cases of poisoning. Magnesium Hydroxide is converted into Magnesium Chloride in
the stomach without forming carbon dioxide
Dosage & Administration
As Laxative:
Adults: 2-4 Tablespoonful with a
full glass of water.
Children: 6-11 years: 1-2
Tablespoonful with a full glass of water. 2-5 years: 1-3 Teaspoonful with a
full glass of water.
As Antacid:
Adults: 1-3 teaspoonful (5 to 15
ml) up to 4 times daily with water.
Children: 1-3 years: ¼
teaspoonful. 3-6 years: ¼-½ teaspoonful. 6-12 years: ½-1 teaspoonful
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Interaction
Magmil can decrease the absorption
of other drugs such as, digoxin, mycophenolate, phosphate supplements (e.g.,
potassium phosphate), tetracycline antibiotics, certain azole antifungals
(ketoconazole, itraconazole), and quinolone antibiotics (e.g., ciprofloxacin,
levofloxacin).
Contraindications
Magnesium Hydroxide should not be
administered where use of laxative is contraindicated. Long term treatment of
Magnesium Hydroxide is contraindicated in patients with renal failure.
Side Effects
Magmil in common with other
magnesium salts may cause diarrhoea.
Precautions & Warnings
The drug should be avoided if
possible in patients with renal and hepatic failure and in those with heart
block and myocardial disease. The drug may be used cautiously in pregnancy.
Therapeutic Class
Antacid with laxative action
Storage Conditions
Store in a cool & dry place,
protected from light. Keep all medicines out of reach of children.
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