UNSAFE
- It is unsafe to consume alcohol
with Aceta.
SAFE IF PRESCRIBED
- Aceta is safe to use during
pregnancy. Most studies have shown low or no risk to the developing baby.
SAFE IF PRESCRIBED
- Aceta is safe to use during
breastfeeding. Human studies suggest that the drug does not pass into the
breastmilk in a significant amount and is not harmful to the baby.
SAFE
- Aceta does not usually affect
your ability to drive.
CAUTION
- Aceta should be used with
caution in patients with kidney disease. Dose adjustment of Aceta may be
needed. Please consult your doctor. However, Aceta contains paracetamol
which is considered the safest painkiller for kidney disease patients.
CAUTION
- Aceta should be used with
caution in patients with liver disease. Dose adjustment of Aceta may be
needed. Please consult your doctor. However, the use of Aceta is not
recommended in patients with severe liver disease and active liver
disease.
Medicine Overview of
Aceta 500mg Tablet
Introduction
Aceta 500mg is a
medicine used to relieve pain and to reduce fever. It is used to treat many
conditions such as headache, body ache, toothache and common cold.Aceta may be
prescr500mg ibed alone or in combination with another medicine. You should take
it regularly as advised by your doctor. It is usually best taken with food
otherwise it may upset your stomach. Do not take more or use it for longer than
recommended. Side effects are rare if this medicine is used correctly but this
medicine may cause stomach pain, nausea, and vomiting in some people. Consult
your doctor if any of these side effects bother you or do not go away.This
medicine is widely prescribed and considered safe but is not suitable for
everybody. Before taking it, let your doctor know if you have liver or kidney
problems or are using blood-thinning medicines. It may affect the dose or
suitability of this medicine. Let your doctor know about all the other
medicines you are taking because they may affect, or be affected by, this
medicine.
Uses of Aceta
Pain relief
Fever
Side effects of Aceta
Common
No common side effects
seen
How to use Aceta
Take Aceta 500mg
medicine in the dose and duration as advised by your doctor. Swallow it as a
whole. Do not chew, crush or break it. Aceta 500mg is to be taken with food.
How Aceta works
Aceta 500mg is an
analgesic (pain reliever) and anti-pyretic (fever reducer). It works by
blocking the release of certain chemical messengers that cause pain and fever.
Aceta is an analgesic (pain reliever) and anti-pyretic (fever reducer). It
works by blocking the release of certain chemical messengers that cause pain
and fever.
What if you forget to
take Aceta?
If you miss a dose of
Aceta 500mg, take it as soon as possible. However, if it is almost time for
your next dose, skip the missed dose and go back to your regular schedule. Do
not double the dose.
Quick Tips
Aceta should be taken
with food or milk to prevent upset stomach.
Take it as per the
dose and duration prescribed by your doctor. Long term use may lead to serious
complications such as stomach bleeding and kidney problems.
Do not take
indigestion remedies (antacids) within two hours of taking Aceta.
Avoid consuming
alcohol while taking this medicine as it can increase your risk of stomach
problems.
Inform your doctor if
you have liver disease as your dose may need to be adjusted.
Your doctor may
regularly monitor your kidney function, liver function and levels of blood
components if you are taking this medicine for long-term treatment.
Brief Description
Indication
Fever, Mild to
moderate pain, osteoarthritis, rheumatoid arthritis, chronic low back pain,
Renal stone pain, neuropathic pain, toothache, migraine, postoperative mild to
moderate pain.
Administration
May be taken with or
without food.
Adult Dose
Oral Mild to moderate
pain and fever Tablet Adult: 1 - 2 tablets every 4 to 6 hours up to a maximum
of 4 g (8 tablets) daily Extended Release (XR) Tablet Adults: 2 tablets,
swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours).
Syrup/Suspension: Adults: 4-8 Measuring spoonful 3-4 times daily; Rectal
Suppository Adults: 500 mg-1 g every 4-6 hours to a maximum of 4 g daily.
Child Dose
Oral Mild to moderate
pain and fever Tablet Children (6 - 12 years) : 1/2 to 1 tablet 3 to 4 times
daily Extended Release (XR) Tablet Children over 12 years: 2 tablets, swallowed
whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). Syrup Mild to
moderate pain and fever Children: 3 months - <1 year : 60 - 120 mg (1/2 - 1
measuring spoonful), 1 - 5 years : 1 - 2 measuring spoonful 6 - 12 years : 2 -
4 measuring spoonful Children: 2 months: 60 mg (1/2 measuring spoonful) for
post immunization pyrexia; Paediatric Drops Mild to moderate pain and fever
Children Up to 3 months: 0.5 ml (40 mg) 4 to 11 months: 1.0 ml (80 mg) 1 to
<2 years: 1.5 ml (120 mg) 2 to 3 years: 2 ml (160mg) 4 to 5 years: 3 ml (240
mg) Dose can be repeated, every 4 hours. Rectal Mild to moderate pain and fever
Suppository Children: 3 months-<1 year: 60-125 mg 1-<5 years: 125-250 mg
5-12 years: 250-500 mg These doses may be repeated every 4-6 hours as necessary
(maximum 4 doses in 24 hours). Children over 12 years: 500 mg-1 g every 4-6
hours to a maximum of 4 g daily. Post-immunisation pyrexia Child: 2-3 mth 60
mg. If necessary, a 2nd dose may be given after 4-6 hr.
Contraindication
Hypersensitivity.
Mode of Action
Paracetamol exhibits
analgesic action by peripheral blockage of pain impulse generation. It produces
antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak
anti-inflammatory activity is related to inhibition of prostaglandin synthesis
in the CNS.
Precaution
Patient w/ chronic
alcoholism, known G6PD deficiency, severe hypovolaemia, chronic malnutrition.
Renal and hepatic impairment. Pregnancy and lactation. Monitoring Parameters
Monitor serum paracetamol levels esp when acute overdosage is suspected and w/
long-term use.
Side Effect
Thrombocytopenia,
leucopenia, pancytopenia, neutropenia, agranulocytosis, pain and burning
sensation at inj site. Rarely, hypotension and tachycardia. Potentially Fatal:
Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised
exanthematous pustulosis, acute renal tubular necrosis and hepatotoxicity.
Interaction
May reduce serum levels w/ anticonvulsants (e.g. phenytoin,
barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin
and other coumarins w/ prolonged use. Accelerated absorption w/ metoclopramide
and domperidone. May increase serum levels w/ probenecid. May increase serum levels
of chloramphenicol. May reduce absorption w/ colestyramine w/in 1 hr of admin.
May cause severe hypothermia w/ phenothiazine.
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