UNSAFE
- It is unsafe to consume alcohol with Renova 500.
SAFE IF PRESCRIBED
- Renova 500 is safe to use during pregnancy. Most studies
have shown low or no risk to the developing baby.
SAFE IF PRESCRIBED
- Renova 500 is safe to use during breastfeeding. Human
studies suggest that the drug does not pass into the breastmilk in a
significant amount and is not harmful to the baby.
SAFE
- Renova 500 does not usually affect your ability to drive.
CAUTION
- Renova 500 should be used with caution in patients with
kidney disease. Dose adjustment of Renova 500 may be needed. Please consult
your doctor. However, Renova 500 contains paracetamol which is considered the
safest painkiller for kidney disease patients.
CAUTION
- Renova 500 should be used with caution in patients with
liver disease. Dose adjustment of Renova 500 may be needed. Please consult your
doctor. However, the use of Renova 500 is not recommended in patients with
severe liver disease and active liver disease.
Medicine Overview of Renova 500mg Tablet
Introduction
- Renova 500 500mg is a medicine used to relieve pain and to
reduce fever. It is used to treat many conditions such as headache, body ache,
toothache and common cold.Renova 500 may be prescr500mg ibed alone or in
combination with another medicine. You should take it regularly as advised by
your doctor. It is usually best taken with food otherwise it may upset your
stomach. Do not take more or use it for longer than recommended. Side effects
are rare if this medicine is used correctly but this medicine may cause stomach
pain, nausea, and vomiting in some people. Consult your doctor if any of these
side effects bother you or do not go away.This medicine is widely prescribed
and considered safe but is not suitable for everybody. Before taking it, let
your doctor know if you have liver or kidney problems or are using
blood-thinning medicines. It may affect the dose or suitability of this
medicine. Let your doctor know about all the other medicines you are taking
because they may affect, or be affected by, this medicine.
Uses of Renova 500
Fever
Side effects of Renova 500
No common side effects seen
How to use Renova 500
- Take Renova 500 500mg medicine in the dose and duration as
advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Renova 500 500mg is to be taken with food.
How Renova 500 works
Renova 500 500mg is an analgesic (pain reliever) and
anti-pyretic (fever reducer). It works by blocking the release of certain
chemical messengers that cause pain and fever. Renova 500 is an analgesic (pain
reliever) and anti-pyretic (fever reducer). It works by blocking the release of
certain chemical messengers that cause pain and fever.
What if you forget to take Renova 500?
If you miss a dose of Renova 500 500mg, take it as soon as
possible. However, if it is almost time for your next dose, skip the missed
dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Renova 500 should be taken with food or milk to prevent
upset stomach.
Take it as per the dose and duration prescribed by your
doctor. Long term use may lead to serious complications such as stomach
bleeding and kidney problems.
Do not take indigestion remedies (antacids) within two hours
of taking Renova 500.
Avoid consuming alcohol while taking this medicine as it can
increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose
may need to be adjusted.
Your doctor may regularly monitor your kidney function,
liver function and levels of blood components if you are taking this medicine
for long-term treatment.
Brief Description
Indication
- Fever, Mild to moderate pain, osteoarthritis, rheumatoid
arthritis, chronic low back pain, Renal stone pain, neuropathic pain,
toothache, migraine, postoperative mild to moderate pain.
Administration
- May be taken with or without food.
Adult Dose
- Oral Mild to moderate pain and fever Tablet Adult: 1 - 2
tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily Extended
Release (XR) Tablet Adults: 2 tablets, swallowed whole, every 6 to 8 hours
(maximum of 6 tablets in any 24 hours). Syrup/Suspension: Adults: 4-8 Measuring
spoonful 3-4 times daily; Rectal Suppository Adults: 500 mg-1 g every 4-6 hours
to a maximum of 4 g daily.
Child Dose
- Oral Mild to moderate pain and fever Tablet Children (6 - 12
years) : 1/2 to 1 tablet 3 to 4 times daily Extended Release (XR) Tablet
Children over 12 years: 2 tablets, swallowed whole, every 6 to 8 hours (maximum
of 6 tablets in any 24 hours). Syrup Mild to moderate pain and fever Children: 3
months - <1 year : 60 - 120 mg (1/2 - 1 measuring spoonful), 1 - 5 years : 1
- 2 measuring spoonful 6 - 12 years : 2 - 4 measuring spoonful Children: 2
months: 60 mg (1/2 measuring spoonful) for post immunization pyrexia;
Paediatric Drops Mild to moderate pain and fever Children Up to 3 months: 0.5
ml (40 mg) 4 to 11 months: 1.0 ml (80 mg) 1 to <2 years: 1.5 ml (120 mg) 2
to 3 years: 2 ml (160mg) 4 to 5 years: 3 ml (240 mg) Dose can be repeated,
every 4 hours. Rectal Mild to moderate pain and fever Suppository Children: 3
months-<1 year: 60-125 mg 1-<5 years: 125-250 mg 5-12 years: 250-500 mg
These doses may be repeated every 4-6 hours as necessary (maximum 4 doses in 24
hours). Children over 12 years: 500 mg-1 g every 4-6 hours to a maximum of 4 g
daily. Post-immunisation pyrexia Child: 2-3 mth 60 mg. If necessary, a 2nd dose
may be given after 4-6 hr.
Hypersensitivity.
Mode of Action
- Paracetamol exhibits analgesic action by peripheral blockage
of pain impulse generation. It produces antipyresis by inhibiting the
hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is
related to inhibition of prostaglandin synthesis in the CNS.
Precaution
- Patient w/ chronic alcoholism, known G6PD deficiency, severe
hypovolaemia, chronic malnutrition. Renal and hepatic impairment. Pregnancy and
lactation. Monitoring Parameters Monitor serum paracetamol levels esp when
acute overdosage is suspected and w/ long-term use.
Side Effect
- Thrombocytopenia, leucopenia, pancytopenia, neutropenia,
agranulocytosis, pain and burning sensation at inj site. Rarely, hypotension
and tachycardia. Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal
necrolysis, acute generalised exanthematous pustulosis, acute renal tubular
necrosis and hepatotoxicity.
Interaction
- May reduce serum levels w/ anticonvulsants (e.g. phenytoin,
barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin
and other coumarins w/ prolonged use. Accelerated absorption w/ metoclopramide
and domperidone. May increase serum levels w/ probenecid. May increase serum
levels of chloramphenicol. May reduce absorption w/ colestyramine w/in 1 hr of
admin. May cause severe hypothermia w/ phenothiazine.
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