CAUTION

• Caution is advised when consuming alcohol with Esoral 40. Please consult your doctor.

CONSULT YOUR DOCTOR

• Esoral 40 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

CONSULT YOUR DOCTOR

• Esoral 40 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

CONSULT YOUR DOCTOR

• It is not known whether Esoral 40 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

SAFE IF PRESCRIBED

• Esoral 40 is safe to use in patients with kidney disease. No dose adjustment of Esoral 40 is recommended. However, inform your doctor if you have any kidney disease.

CAUTION

• Esoral 40 should be used with caution in patients with severe liver disease. Dose adjustment of Esoral 40 may be needed. Please consult your doctor.
• Medicine Overview of Esoral 40mg Tablet

Introduction

• Esoral 40 is a medicine which reduces the amount of acid produced in your stomach. It is used to treat heartburn, acid reflux and problems in your food pipe. It is also used to prevent and treat stomach ulcers. You should take Esoral 40 as your doct.

Uses of Esoral 40

• Gastroesophageal reflux disease (Acid reflux)
• Peptic ulcer disease

Side effects of Esoral 40

• Common
• Headache
• Dizziness
• Dryness in mouth
• Nausea
• Abdominal pain
• Constipation
• Flatulence
• Diarrhea

How to use Esoral 40

• Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esoral 40 is to be taken empty stomach.

How Esoral 40 works

• Esoral 40 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

What if you forget to take Esoral 40?

• If you miss a dose of Esoral 40, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

• It is a well-tolerated medicine and provides relief for a long time.
• Avoid eating late at night or before bedtime.
• Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
• Long-term use of Esoral 40 can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and ...
• Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue..
• Brief Description

Indication

• Heartburn, Acid Related Dyspepsia, Peptic ulcer disease, Zollinger-Ellison syndrome, Gastroesophageal reflux disease (GERD), Helicobacter pylori infec...

Administration

• Delayed-release cap: Should be taken on an empty stomach. Take on an empty stomach 1 hr before meals. Tab: May be taken with or without food.

Adult Dose

• GERD Without Erosive Esophagitis 20 mg PO qDay for 4 weeks; consider an additional 4 weeks of treatment if symptoms do not resolve completely in the ...

Child Dose

• GERD Without Erosive Esophagitis Oral <1 year: Safety and efficacy not established 1-12 years: 10-20 mg PO qDay for up to 8 weeks >12 years: 20-40...
• Renal Dose
• Renal impairment: No dosage adjustment needed.

Contraindication

• Esomeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted Benzimidazoles.

Mode of Action

• Esomeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell. It is the S-isomer of omeprazole...

Precaution

• Paediatric; pregnancy, lactation. Malignancy and hepatic impairment. Increased risk of developing certain infections such as community-acquired pneumo...

Side Effect

• >10% Headache (2-11%) 1-10% Flatulence (10%),Indigestion (6%),Nausea (6%),Abdominal pain (1-6%),Diarrhea (2-4%),Xerostomia (3-4%),Dizziness (2-3%.

Pregnancy Category Note

• Pregnancy There are no adequate and well-controlled studies in pregnant women; esomeprazole is the S-isomer of omeprazole; available epidemiologic da..

Interaction

• Increased risk of digoxin-induced cardiotoxic effects. Increased risk of hypomagnesaemia w/ diuretics. May increase INR and prothrombin time w/ warfar...