Indications
Biokof is used to relieve dry
(non-productive) cough. Dry cough may be caused by a recent viral infection.
Biokof is also used for pre & post-operative cough sedation in patients who
will undergo surgical procedures and bronchoscopy. It can be used in the acute
cough of any etiology, whooping cough and cough due to acute lower respiratory
tract infections (tracheitis, laryngitis, bronchitis) etc.
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Pharmacology
Butamirate Citrate acts directly
on the brain's cough center to suppress cough. Butamirate Citrate is safe and
non-sedating which is neither chemically nor pharmacologically related to opium
alkaloids. Butamirate Citrate is rapidly and completely absorbed after oral
administration. Maximum concentration is reached within 9 hours with the
sustained-release tablet. This is extremely protein-bound and plasma
elimination half-life is about 13 hours. The active metabolites of Butamirate
Citrate have also antitussive action.
Dosage & Administration
Use in adult:
Butamirate Citrate 50 mg tablet:
2-3 tablets daily.
Butamirate Citrate syrup: 15 ml 4
times daily.
Use in children &
adolescents:
Butamirate Citrate 50 mg tablet:
Adolescent over 12 years old: 1-2
tablets daily.
Butamirate Citrate syrup:
Children (3-6 yrs): 5 ml 3 times
daily.
Children (6-12 yrs): 10 ml 3
times daily.
Adolescent: 15 ml 3 times daily.
Butamirate Citrate pediatric drops:
Children ( 2 months- 1 yrs): 0.50
ml 4 times daily.
Children (1-3 yrs): 0.75 ml 4
times daily.
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Interaction
Concomitant use with expectorants
should be avoided.
Contraindications
Hypersensitivity to the active
ingredient.
Side Effects
Tolerance of Biokof is
good.Adverse reactions such as rash,nausea,diarrhoea and vertigo have been
observed in a few rare cases,resolving after dose reduction or treatment
withdrawal.
Pregnancy & Lactation
Butamirate Citrate should not be
used during the first trimester of pregnancy. During the remainder of
pregnancy, it can be used if indicated by a physician but with caution. As a
general rule, for safety reasons, in the absence of data on elimination of the
active substance in breast milk, the benefits of Butamirate Citrate
administration during breast feeding should be carefully weighed against the
risks.
Precautions & Warnings
Biokof suppresses the cough
reflex and therefore the concomitant use with expectorants should be avoided,
since it may lead to mucus retention in the airways, which increases the risk
of bronchospasm and respiratory infections. If the cough persists for more than
7 days (more than 3 days in children younger than12 years of age) doctor must
be consulted.
Overdose Effects
Accidental overdose with Biokof
can cause the following symptoms: drowsiness, nausea, vomiting, diarrhoea, loss
of balance and hypotension. Standard emergency procedures should be followed:
activated charcoal, saline laxatives and standard cardio-respiratory
resuscitation.
Therapeutic Class
Cough suppressant
Storage Conditions
Keep away from light and
moisture, store below 30°C. Keep all the medicines out of the reach of
children.
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