Indications
Azolin is indicated for the
treatment of nasal congestion associated with acute or chronic rhinitis, common
cold, sinusitis, upper respiratory allergies, epistaxis and hay fever. It is
also used as nasal decongestant in otitis media.
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Pharmacology
Oxymetazoline Hydrochloride is an
imidazoline derivative sympathomimetic amine. It is a direct agonist at
α-adrenoceptors but has no action on β- adrenoceptors. It is used as a topical
agent on the nasal mucosa, produces a rapid and long acting vasoconstriction of
the arterioles, thus reducing the blood flow and diminishing swelling of the
mucosa. This results in improved potency of the airway and better drainage of
the nasal sinus.
Dosage
Oxymetazoline nasal spray-
Adults and children (6 years of
age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
Elderly: There is no need for
dosage reduction in the elderly for nasal administration.
Children below 6 years of age: It
is not suitable for children below 6 years of age.
Oxymetazoline nasal drop-
Adults & children 6 years of
age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning
and evening.
Children 2-5 years of age: 2-3
drops of 0.025% Nasal Drops in each nostril twice daily in the morning and
evening
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Administration
How to use the Nasal Spray-
Shake the bottle gently and
remove the dust cover.
Hold the spray with your
forefinger and middle finger on either side of the nozzle and your thumb
underneath the bottle. Press down until a fine spray appears. If using for the
first time or if you have not used it for a week or more, press the nasal
applicator several times until a fine moist comes out from the container.
Gently blow the nose to clear the
nostrils.
Close one nostril and carefully
insert the nasal applicator into the open nostril. Tilt your head forward
slightly and keep the spray upright. Breathe in through your nose and while
breathing in, press the white-collar of nasal applicator firmly down once to
release a spray.
Breathe out through your mouth.
Repeat the above steps in the
same/ other nostril for consecutive doses.
Cleaning: The nasal spray should
be cleaned at least once a week. The procedures are as follows-
Remove the dust cover.
Gently pull off the nasal
applicator.
Wash the applicator and dust
cover in warm water.
Shake off the excess water and
leave to dry in a normal place. Avoid to apply additional heat.
Gently push the applicator back
on the top of the bottle and re-fix the dust cover.
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Interaction
Azolin loride Nasal preparation
should not be given to patients being treated with MAO inhibitors or within 14
days of ceasing such treatment.
Contraindications
It is contraindicated in patients
with cardiovascular disease, hyperthyroidism, prostatic enlargement, angle
closure glaucoma and hypersensitivity to any of its ingredients.
Side Effects
Occasionally it may cause local
irritation and dryness of the mouth and throat. Temporarily discomfort such as
burning, stinging, sneezing or increase in nasal discharge may occur.
Pregnancy & Lactation
The safety of Oxymetazoline
Hydrochloride Nasal Spray during pregnancy and lactation has not been
established, but is not thought to constitute a hazard during those periods.
Precautions & Warnings
Keep away from the eyes. The
spray should not be used for longer than seven days without medical advice.
Frequent or prolonged use may cause nasal congestion to recur or worsen.
Overdose Effects
Overdose may give rise to local
irritation and rebound congestion. Treatment need only be symptomatic.
Therapeutic Class
Nasal Anti-histamine
preparations, Nasal Decongestants & Other Nasal Preparations
Storage Conditions
Keep below 30° C temperature in a
dry place, protect from light. Do not refrigerate or freeze. Keep out of the
reach of children.
english
