Indications
Aluminium Hydroxide and Magnesium
Hydroxide is indicated for Hyperacidity, peptic ulcer, gastritis, heartburn,
sour stomach & dyspepsia.
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Composition
Each tablet contains-
Dried Aluminium Hydroxide Gel BP
(Al2O3 47%, minimum): 250 mg
Magnesium Hydroxide BP: 400 mg
Each 5 ml contains-
Aluminium Oxide (Equivalent
amount of Aluminium Hydroxide Gel USP): 175 mg
Magnesium Hydroxide (Equivalent
amount of Magnesium Hydroxide Paste USP): 225 mg
Pharmacology
This drug is well-balanced combination of essential non-systemic antacids which excel in efficacy and palatability. These are dependable antacid preparations without acid rebound, constipating or cathertic effects. Both the preparations provide symptomatic relief of hyperacidity associated with heartburn, acid ingestion or sour stomach.
Aluminium hydroxide gel, a slow
acting antacid and an adsorbent with prolonged effect, has high neutralizing
power. Magnesium Hydroxide possesses a slow but sustained acid neutralizing property.
Antacids of both tablet and suspension possess adsorbent property. They form a
protecting coating over the ulcer surface facilitating its healing; thus
protecting the sensitive mucosa of stomach and duodenum from further
irritation.
Dosage & Administration
Tablet: Two tablets 1-3 hours after meal and at bed time or as directed by the physician.
Suspension: 2 tea spoonful 1-3
hours after meal and at bed time or as directed by the physician.
* রেজিস্টার্ড
চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Interaction
Antanil inhibits the absorption
of following drugs: Azithromycin, cefpodoxime, ciprofloxacin, isoniazid,
rifampicin, norfloxacin, ofloxacin, pivampicillin, tetracyclines, Gabapentin
and phenytoin, Itraconazole, ketoconazole, Chloroquine, hydroxychloroquine and
Phenothiazines.
Contraindications
This is contraindicated in
hypophosphataemia. It is also contraindicated in alkalosis and hypermagnesaemia
where abdominal distention may be due to partial or complete intestinal
obstruction.
Side Effects
Long term use of any antacid
results in alkaluria, which may predispose to nephrolithiasis by forming
precipitation of calcium phosphate.
Pregnancy & Lactation
It is advised to avoid antacid
preparations in the first trimester of pregnancy.
Precautions & Warnings
Antacids reduce the absorption of
tetracycline when given concomitantly. These should not be used concomitantly
Therapeutic Class
Antacids
Storage Conditions
Keep below 30°C temperature, away
from light & moisture. Keep out of the reach of children.
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